Interferon Independent Non-Canonical STAT Activation and Virus Induced Inflammation

@inproceedings{Nan2018InterferonIN,
  title={Interferon Independent Non-Canonical STAT Activation and Virus Induced Inflammation},
  author={Yuchen Nan and Chunyan Wu and Yanjin Zhang},
  booktitle={Viruses},
  year={2018}
}
Interferons (IFNs) are a group of secreted proteins that play critical roles in antiviral immunity, antitumor activity, activation of cytotoxic T cells, and modulation of host immune responses. IFNs are cytokines, and bind receptors on cell surfaces to trigger signal transduction. The major signaling pathway activated by IFNs is the JAK/STAT (Janus kinase/signal transducer and activator of transcription) pathway, a complex pathway involved in both viral and host survival strategies. On the one… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 183 REFERENCES

Interferon Induction by RNA Viruses and Antagonism by Viral Pathogens

Yuchen Nan, Guoxin Nan, Yan-Jin Zhang
  • Viruses
  • 2014
VIEW 11 EXCERPTS
HIGHLY INFLUENTIAL

STAT2 phosphorylation and signaling

VIEW 17 EXCERPTS
HIGHLY INFLUENTIAL

Constitutive nuclear import of latent and activated STAT5a by its coiled coil domain.

  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 2008
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

SOCS regulation of the JAK/STAT signalling pathway.

  • Seminars in cell & developmental biology
  • 2008
VIEW 15 EXCERPTS
HIGHLY INFLUENTIAL

Mechanisms of type-I- and type-II-interferon-mediated signalling

  • Nature Reviews Immunology
  • 2005
VIEW 14 EXCERPTS
HIGHLY INFLUENTIAL

STAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-alpha3.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2005
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

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