Interferon-Gamma Release Assay Performance of Pleural Fluid and Peripheral Blood in Pleural Tuberculosis

@inproceedings{Liu2013InterferonGammaRA,
  title={Interferon-Gamma Release Assay Performance of Pleural Fluid and Peripheral Blood in Pleural Tuberculosis},
  author={Fei Liu and Mengqiu Gao and Xia Zhang and Fengjiao Du and Hongyan Jia and Xinting Yang and Zitong Wang and Liqun Zhang and Liping Ma and Xiaoguang Wu and Li Xie and Zongde Zhang},
  booktitle={PloS one},
  year={2013}
}
BACKGROUND The diagnosis of pleural tuberculosis (TB) remains to be difficult. Interferon-gamma release assay (IGRA) is a promising method for diagnosing TB in low TB burden countries. The release of interferon-gamma (IFN-γ) by T lymphocytes increases at a localized site of infection with Mycobacterium tuberculosis antigen. This study aimed to examine the clinical accuracy of T-SPOT.TB on pleural fluid and peripheral blood for the diagnosis of pleural TB in high TB burden country. METHODS 168… CONTINUE READING

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