Interferon-γ release assays versus tuberculin skin test for targeting people for tuberculosis preventive treatment: an evidence-based review.

@article{Muoz2013InterferonRA,
  title={Interferon-γ release assays versus tuberculin skin test for targeting people for tuberculosis preventive treatment: an evidence-based review.},
  author={Laura Mu{\~n}oz and M Santin},
  journal={The Journal of infection},
  year={2013},
  volume={66 4},
  pages={
          381-7
        }
}
OBJECTIVES To assess whether Interferon-γ release assays (IGRAs) reduce the number of people considered for tuberculosis (TB) preventive treatment without increasing subsequent active disease. METHODS Longitudinal studies with both tuberculin skin test (TST) and IGRAs were identified through a PubMed search. Reductions in diagnosis of TB infection and increases in incident TB in people considered not infected, using IGRAs either instead of TST or as a confirmatory test (two-step approach… CONTINUE READING
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