Interferon-γ +874A/T polymorphism in relation to generalized chronic periodontitis and the presence of periodontopathic bacteria.

@article{Holla2011InterferonP,
  title={Interferon-γ +874A/T polymorphism in relation to generalized chronic periodontitis and the presence of periodontopathic bacteria.},
  author={Lydie Izakovicova Holla and Barbara Hrdlickov{\'a} and Petra Borilova Linhartova and Anton{\'i}n Fassmann},
  journal={Archives of oral biology},
  year={2011},
  volume={56 2},
  pages={153-8}
}
BACKGROUND Interferon gamma (IFN-γ) is one of the key regulatory cytokines that has a significant effect on immune responses. It may be important in the chronic inflammatory diseases such as periodontitis in which increased IFN-γ levels were found. The aim of this study was to analyze +874A/T polymorphism in the IFN-γ gene and its associations with the presence of periodontopathic bacteria and susceptibility to generalized chronic periodontitis (CP). METHODS A total of 498 unrelated Czech… CONTINUE READING
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