Interferon-α-Induced Depression: When a Randomized Trial Is Not a Randomized Controlled Trial

  title={Interferon-$\alpha$-Induced Depression: When a Randomized Trial Is Not a Randomized Controlled Trial},
  author={Gopinath Ranjith},
  journal={Psychotherapy and Psychosomatics},
  pages={387 - 387}
  • G. Ranjith
  • Published 1 October 2005
  • Medicine
  • Psychotherapy and Psychosomatics
Patten and Barbui [1] have performed a singular service to the profession by carrying out a systematic review on drug-induced depression. Their recommendations are based on studies that have randomly allocated patients into study and control groups, and the authors have provided an adequate justifi cation for this being the most scientifi c approach. This letter is to point out that the authors have erroneously designated a study as a randomized controlled trial. The authors state that… 

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