Interferon-&ggr; Axis in Graft Arteriosclerosis

@article{Tellides2007InterferonggrAI,
  title={Interferon-\&ggr; Axis in Graft Arteriosclerosis},
  author={George Tellides and Jordan S. Pober},
  journal={Circulation Research},
  year={2007},
  volume={100},
  pages={622-632}
}
Cardiac transplantation is the most effective treatment for advanced heart failure. Despite improvements in immunosuppression therapy that prevent acute rejection, cardiac allografts fail at rates of 3% to 5% per posttransplant year. The hallmark morphological lesion of chronically failing cardiac allografts, also seen in chronic renal and liver graft failure, is luminal stenosis of blood vessels, especially of conduit arteries. Late graft failure results from widespread secondary ischemic… 

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