Interferon‐λs: the modulators of antivirus, antitumor, and immune responses

@article{Li2009InterferonsTM,
  title={Interferon‐$\lambda$s: the modulators of antivirus, antitumor, and immune responses},
  author={Mingcai Li and Xiaojin Liu and Yan-chun Zhou and Shao Bo Su},
  journal={Journal of Leukocyte Biology},
  year={2009},
  volume={86}
}
IFN‐λs, including IFN‐λ1, IFN‐λ2, and IFN‐λ3, also known as IL‐29, IL‐28A, or IL‐28B, are a newly described group of cytokines distantly related to the type I IFNs and IL‐10 family members. The IFN‐λR complex consists of a unique ligand‐binding chain, IFN‐λR1 (also designated IL‐28Rα), and an accessory chain, IL‐10R2, which is shared with receptors for IL‐10‐related cytokines. IFN‐λs signal through the IFN‐λR and activate pathways of JAK‐STATs and MAPKs to induce antiviral, antiproliferative… 
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