Interference on cytoplasmic polyadenylation element-binding proteins affects the invasion ability of glioma stem cells.

@article{Liu2015InterferenceOC,
  title={Interference on cytoplasmic polyadenylation element-binding proteins affects the invasion ability of glioma stem cells.},
  author={Honglin Liu and Jinlong Huo and Z J Liu and Xiao-bing Chen},
  journal={Genetics and molecular research : GMR},
  year={2015},
  volume={14 4},
  pages={13504-10}
}
Glioma stem cells derived from primary cultures were divided into an experiment group, a control group, and a blank group and subjected to cytoplasmic polyadenilation element-binding protein (CPEBs) interference, transfection with empty vector, and normal culture, respectively, to compare their invasion abilities. Western blotting showed that siRNA-3 had the strongest interfering effect on CPEBs. CPEBs were expressed in the experiment group with green fluorescence at an expression rate of over… CONTINUE READING