Interference of magnetic resonance imaging contrast agents with the serum calcium measurement technique using colorimetric reagents.

@article{Lin1999InterferenceOM,
  title={Interference of magnetic resonance imaging contrast agents with the serum calcium measurement technique using colorimetric reagents.},
  author={J Lin and J M Id{\'e}e and Marc Port and A Diai and Christine Berthommier and Michel Robert and Isabelle Raynal and Ludovic Devoldere and Claire A Corot},
  journal={Journal of pharmaceutical and biomedical analysis},
  year={1999},
  volume={21 5},
  pages={931-43}
}
A possible interaction between either linear (Gd-DTPA-BMA and Gd-DTPA) or macrocyclic (Gd-DOTA) gadolinium complexes used as magnetic resonance imaging (MRI) contrast agents and colorimetric technique reagents for the measurement of serum calcium was evaluated on human serum pools, and its mechanism was investigated by means of UV spectrometry and electro-spray ionization mass spectrometry (ESI-MS). The highest concentration tested was 2.5 mM (corresponding to a putative strictly intravascular… CONTINUE READING
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