Interference in the endplate nutritional pathway causes intervertebral disc degeneration in an immature porcine model

@article{Kang2014InterferenceIT,
  title={Interference in the endplate nutritional pathway causes intervertebral disc degeneration in an immature porcine model},
  author={Ran Kang and Haisheng Li and Steffen Ringgaard and Kresten Rickers and Haolin Sun and Muwan Chen and Lin Xie and Cody B{\"u}nger},
  journal={International Orthopaedics},
  year={2014},
  volume={38},
  pages={1011-1017}
}
Previous studies have shown that blocking the endplate nutritional pathway with bone cement did not result in obvious intervertebral disc degeneration (IDD) in mature animal models. However, there are very few comparable studies in immature animal models. As vertebroplasty currently is beginning to be applied in young, even biologically immature patients, it is important to investigate the effect of cement blocking at the endplate in an immature animal model. Two lumbar intervertebral discs in… CONTINUE READING

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