Interference from anti-streptavidin antibody.

  title={Interference from anti-streptavidin antibody.},
  author={Nichole Johnson Rulander and D. Cardamone and Marilyn B Senior and Peter J. Snyder and Stephen R. Master},
  journal={Archives of pathology & laboratory medicine},
  volume={137 8},
Immunoassays are commonly used for clinical diagnosis, although interferences have been well documented. The streptavidin-biotin interaction provides an efficient and convenient method to manipulate assay components and is currently used in several immunoassay platforms. To date, there has been no report in the literature of interference from endogenous anti-streptavidin antibodies; however, such antibodies would potentially affect multiple diagnostic platforms. We report results from a patient… CONTINUE READING

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