Interference among deleterious mutations favours sex and recombination in finite populations
@article{Keightley2006InterferenceAD, title={Interference among deleterious mutations favours sex and recombination in finite populations}, author={P. Keightley and S. Otto}, journal={Nature}, year={2006}, volume={443}, pages={89-92} }
Sex and recombination are widespread, but explaining these phenomena has been one of the most difficult problems in evolutionary biology. Recombination is advantageous when different individuals in a population carry different advantageous alleles. By bringing together advantageous alleles onto the same chromosome, recombination speeds up the process of adaptation and opposes the fixation of harmful mutations by means of Muller's ratchet. Nevertheless, adaptive substitutions favour sex and… CONTINUE READING
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References
SHOWING 1-10 OF 36 REFERENCES
SELECTION FOR RECOMBINATION IN SMALL POPULATIONS
- Biology, Medicine
- Evolution; international journal of organic evolution
- 2001
- 230
- PDF
Selection on a modifier of recombination rate due to linked deleterious mutations.
- Biology, Medicine
- The Journal of heredity
- 2002
- 11
Evolution of genetic variability and the advantage of sex and recombination in changing environments.
- Biology, Medicine
- Genetics
- 1999
- 140
- PDF
Mutation-selection balance and the evolutionary advantage of sex and recombination.
- Biology, Medicine
- Genetical research
- 1990
- 378
- PDF
The evolutionary advantage of recombination. II. Individual selection for recombination.
- Biology, Medicine
- Genetics
- 1976
- 180
- PDF
Deleterious mutations as an evolutionary factor. 1. The advantage of recombination.
- Medicine, Biology
- Genetical research
- 1984
- 174