Interfamily transfer of a plant pattern-recognition receptor confers broad-spectrum bacterial resistance

@article{Lacombe2010InterfamilyTO,
  title={Interfamily transfer of a plant pattern-recognition receptor confers broad-spectrum bacterial resistance},
  author={Severine Lacombe and Alejandra Rougon-Cardoso and Emma J Sherwood and Nemo Peeters and Douglas Dahlbeck and H. Peter van Esse and Matthew Smoker and Ghanasyam Rallapalli and Bart P.H.J. Thomma and Brian J. Staskawicz and Jonathan D. G. Jones and Cyril Zipfel},
  journal={Nature Biotechnology},
  year={2010},
  volume={28},
  pages={365-369}
}
Plant diseases cause massive losses in agriculture. Increasing the natural defenses of plants may reduce the impact of phytopathogens on agricultural productivity. Pattern-recognition receptors (PRRs) detect microbes by recognizing conserved pathogen-associated molecular patterns (PAMPs). Although the overall importance of PAMP-triggered immunity for plant defense is established, it has not been used to confer disease resistance in crops. We report that activity of a PRR is retained after its… 
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References

SHOWING 1-10 OF 34 REFERENCES
Bacterial disease resistance in Arabidopsis through flagellin perception
TLDR
It is shown that treatment of plants with flg22, a peptide representing the elicitor-active epitope of flagellin, induces the expression of numerous defence-related genes and triggers resistance to pathogenic bacteria in wild-type plants, but not in plants carrying mutations in the flageLLin receptor gene FLS2.
Plant immunity: a lesson from pathogenic bacterial effector proteins
TLDR
This review focuses on how studies have conceptually advanced the understanding of plant–pathogen interactions and a variety of biochemical properties to directly attack key components of PAMP‐triggered immunity and effector‐trIGgered immunity are attacked.
Early events in the pathogenicity of Pseudomonas syringae on Nicotiana benthamiana.
TLDR
It is shown here that the solanaceous species Nicotiana benthamiana perceives the flagellin proteins of both pathogenic and non-host species of Pseudomonas syringae, and this observation separates the respective mechanisms of the two effectors, and suggests that AvrPtoB may target the defence machinery directly for its suppressive effect.
The LysM receptor kinase CERK1 mediates bacterial perception in Arabidopsis
TLDR
Reduced activation of a PAMP-induced defence response on plants lacking the CERK1 gene after treatment with crude bacterial extracts demonstrates that C ERK1 mediates perception of an unknown bacterial PAMP in Arabidopsis.
The plant immune system
TLDR
A detailed understanding of plant immune function will underpin crop improvement for food, fibre and biofuels production and provide extraordinary insights into molecular recognition, cell biology and evolution across biological kingdoms.
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