Interfaces to connect thin-layer chromatography with electrospray ionization mass spectrometry.

@article{Hsu2003InterfacesTC,
  title={Interfaces to connect thin-layer chromatography with electrospray ionization mass spectrometry.},
  author={Feng-Liu Hsu and Chun-Hsien Chen and Cheng-Hui Yuan and Jentaie Shiea},
  journal={Analytical chemistry},
  year={2003},
  volume={75 10},
  pages={2493-8}
}
This study has developed two interfaces to connect small-size thin-layer chromatography (TLC) with electrospray ionization mass spectrometry (ES-MS) for the continuous analysis of organic mixtures. The interfaces are (1) two bound optical fibers inserted into the C18-bonded particles at the exit of a small TLC channel and (2) a small commercial TLC strip with a sharpened tip. A reservoir continuously supplied a makeup solution to the tip of the TLC channel. The high voltage required for… CONTINUE READING