Interfaces between allergen structure and diagnosis: know your epitopes.

  title={Interfaces between allergen structure and diagnosis: know your epitopes.},
  author={Anna Pom{\'e}s and Maksymilian Chruszcz and Alla Gustchina and Alexander Wlodawer},
  journal={Current allergy and asthma reports},
  volume={15 8},
Allergy diagnosis is based on the patient's clinical history and can be strengthened by tests that confirm the origin of sensitization. In the past 25 years, these tests have evolved from the exclusive in vivo or in vitro use of allergen extracts, to complementary molecular-based diagnostics that rely on in vitro measurements of IgE reactivity to individual allergens. For this to occur, an increase in our understanding of the molecular structure of allergens, largely due to the development of… CONTINUE READING
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