Interface integration of layered collagen scaffolds with defined matrix stiffness: implications for sheet-based tissue engineering.

@article{Hadjipanayi2009InterfaceIO,
  title={Interface integration of layered collagen scaffolds with defined matrix stiffness: implications for sheet-based tissue engineering.},
  author={Ektoras Hadjipanayi and Robert A.M. Brown and Vivek C Mudera},
  journal={Journal of tissue engineering and regenerative medicine},
  year={2009},
  volume={3 3},
  pages={230-41}
}
Successful application of sheet-based engineering for complex tissue reconstruction requires optimal integration of construct components. An important regulator of cellular responses (such as migration and collagen deposition) mediating interface integration is matrix stiffness. In this study we developed a sheet-based 3D model of interface integration that allows control of interface matrix stiffness. Fluid was removed from acellular or fibroblast-seeded bilayer collagen hydrogel constructs… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 40 references

Reconstruction of functional tissues with cell sheet engineering.

Biomaterials • 2007
View 17 Excerpts
Highly Influenced

Ultrarapid engineering of biomimetic materials and tissues: fabrication of nano- and microstructures by plastic compression

RA Brown, M Wiseman, CB Chuo
Adv Funct Mater • 2005
View 15 Excerpts
Highly Influenced

A completely biological tissue-engineered human blood vessel.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology • 1998
View 4 Excerpts
Highly Influenced

Engineering graded tissue interfaces.

Proceedings of the National Academy of Sciences of the United States of America • 2008
View 1 Excerpt

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