Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia.

@article{Merkel2010InterdependentRO,
  title={Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia.},
  author={Olaf Merkel and Daniela Asslaber and Josefina D. Pi{\~n}{\'o}n and Alexander Egle and Richard Greil},
  journal={Cell cycle},
  year={2010},
  volume={9 14},
  pages={2764-8}
}
Chronic lymphocytic leukemia (CLL) has an incidence 4/1,00,000 people in the western world and is one of the first cancers reported to be associated with deregulated miRNA expression. microRNAs are small non coding RNAs that are important regulators of protein expression through binding to their untranslated 3'-UTR region. The miR-34 family was demonstrated… CONTINUE READING