Intercepting pelvic cancer in the distal fallopian tube: theories and realities.

@article{Crum2009InterceptingPC,
  title={Intercepting pelvic cancer in the distal fallopian tube: theories and realities.},
  author={Christopher P Crum},
  journal={Molecular oncology},
  year={2009},
  volume={3 2},
  pages={165-70}
}
The pathogenesis of high-grade serous carcinoma of the ovary has come into sharper focus as closer attention has been paid to the earlier phases of this disease. The study of patients with BRCA mutation has been of particular value, in as much as the examination of prophylactic salpingo-oophorectomies will reveal an early cancer in approximately 5% of individuals. Recently studies have shown that about 80% of these early carcinomas originate in the distal fallopian tube. This review summarizes… CONTINUE READING