Intercellular signaling pathways active during intervertebral disc growth, differentiation, and aging.

@article{Dahia2009IntercellularSP,
  title={Intercellular signaling pathways active during intervertebral disc growth, differentiation, and aging.},
  author={Chitra Lekha Dahia and Eric J. Mahoney and Atiq A Durrani and Christopher C. Wylie},
  journal={Spine},
  year={2009},
  volume={34 5},
  pages={456-62}
}
STUDY DESIGN Intervertebral discs at different postnatal ages were assessed for active intercellular signaling pathways. OBJECTIVE To generate a spatial and temporal map of the signaling pathways active in the postnatal intervertebral disc (IVD). SUMMARY OF BACKGROUND DATA The postnatal IVD is a complex structure, consisting of 3 histologically distinct components, the nucleus pulposus, fibrous anulus fibrosus, and endplate. These differentiate and grow during the first 9 weeks of age in… CONTINUE READING

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