Intercellular coupling mechanism for synchronized and noise-resistant circadian oscillators.

@article{Ueda2002IntercellularCM,
  title={Intercellular coupling mechanism for synchronized and noise-resistant circadian oscillators.},
  author={Hiroki R Ueda and Kenzo Hirose and Masamitsu Iino},
  journal={Journal of theoretical biology},
  year={2002},
  volume={216 4},
  pages={501-12}
}
The circadian clock in multicellular organisms consists of multiple autonomous single-cell oscillators. These individual oscillator cells produce coherent oscillations even in the presence of internal noise associated with rhythm-generating reaction rates and in the absence of external time cues such as light and temperature. Thus, an intercellular coupling… CONTINUE READING