Intercellular adhesion molecule-1 mediated interactions and leucocyte infiltration in IgA nephropathy.

@article{Arrizabalaga1997IntercellularAM,
  title={Intercellular adhesion molecule-1 mediated interactions and leucocyte infiltration in IgA nephropathy.},
  author={Pilar Arrizabalaga and Manuel Sol{\'e} and Ileana Quinto and Carlos Ascaso},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={1997},
  volume={12 11},
  pages={2258-62}
}
BACKGROUND Mononuclear leucocytes have a role in IgA nephropathy (IgAN). Renal leucocyte recruitment is mediated by adhesive interactions between leucocytes and their ligands on renal cells. METHODS We have assessed interstitial and glomerular leucocytes by avidin-biotin-peroxidase with monoclonal antibodies (MA) against leucocytes (CD45), beta 2-integrin (CD18), monocyte-macrophages (CD14), T (CD3) and T-cell subsets (CD4, CD8), and intercellular adhesion molecule-1 (ICAM-1) (CD54), and… CONTINUE READING

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