Intercellular adhesion molecule-1 (ICAM-1)-dependent and ICAM-1-independent adhesive interactions between polymorphonuclear leukocytes and human airway epithelial cells infected with parainfluenza virus type 2.

@article{Tosi1992IntercellularAM,
  title={Intercellular adhesion molecule-1 (ICAM-1)-dependent and ICAM-1-independent adhesive interactions between polymorphonuclear leukocytes and human airway epithelial cells infected with parainfluenza virus type 2.},
  author={Michael F Tosi and James M Stark and Ali G. Hamedani and Clifton Smith and Dieter C. Gruenert and Yung T. Huang},
  journal={Journal of immunology},
  year={1992},
  volume={149 10},
  pages={3345-9}
}
Acute respiratory virus infections are often associated with an early influx of neutrophils (PMN) into the airways. Maximal cytoxic injury by PMN depends on tight cell-cell adhesion. Infection of some cell types by respiratory and other viruses has been shown to increase PMN adhesion to these cells by undefined mechanisms. We studied adhesion by human PMN… CONTINUE READING