Interatrial conduction in the mechanisms of atrial fibrillation: from anatomy to cardiac signals and new treatment modalities.

@article{Platonov2007InteratrialCI,
  title={Interatrial conduction in the mechanisms of atrial fibrillation: from anatomy to cardiac signals and new treatment modalities.},
  author={Pyotr G. Platonov},
  journal={Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology},
  year={2007},
  volume={9 Suppl 6},
  pages={
          vi10-6
        }
}
  • P. Platonov
  • Published 1 November 2007
  • Medicine
  • Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
Areas of slow conduction and conduction block are important prerequisites for re-entry known to underlie atrial fibrillation (AF). Experimental and clinical data show that AF is associated with global lowering of atrial propagation velocity and the presence of defects in the interatrial conduction routes. The increasing data from anatomical studies demonstrate the possible prerequisites for conduction disturbances that could be primarily because of anatomical variability in interatrial… 
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Interatrial conduction in patients with paroxysmal atrial fibrillation and in healthy subjects.
Influence of the earliest right atrial activation site and its proximity to interatrial connections on P-wave morphology.
TLDR
The electrical contributor's site of earliest activation and intactness of posterior IACs affect PTF-V1 significantly by changing LA breakthrough sites independent from LA size, which should be considered for interpretation of electrocardiographical signs of LA abnormality and LA enlargement.
Chronotropic Modulation of the Source-Sink Relationship of Sinoatrial-Atrial Impulse Conduction and Its Significance to Initiation of AF: A One-Dimensional Model Study
Initiation and maintenance of atrial fibrillation (AF) is often associated with pharmacologically or pathologically induced bradycardic states. Even drugs specifically developed in order to…
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Atrial fibrillation is a supraventricular tachyarrhythmia characterized by uncoordinated atrial activation with consequent deterioration of atrial mechanical function and increases with age, reaching 8% in patients older than 80 years.
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TLDR
It is demonstrated that left atrial myocardium with increased gadolinium uptake has lower local conduction velocity, which may facilitate the targeting of the substrate for reentrant arrhythmias.
Atrial Electromehanical Interval Using Tissue Doppler as Predictor of Atrial Fibrillation After Coronary Artery Bypass Grafting
TLDR
The interval of Electromechanical in the lateral left atrium using tissue dopper echocardiography can predict the occurrence of AF post CABG.
Interatrial Block Predicts Atrial Fibrillation and Total Mortality in Patients with Cardiac Resynchronization Therapy
TLDR
IAB is associated with new-onset atrial fibrillation and death in CRT recipients and may be helpful in the risk stratification in the context of heart failure management, and Abnormal PTFV1 did not demonstrate any prognostic value.
Short P‐Wave Duration is a Marker of Higher Rate of Atrial Fibrillation Recurrences after Pulmonary Vein Isolation: New Insights into the Pathophysiological Mechanisms Through Computer Simulations
TLDR
Computer simulations suggest that shortening of atrial action potential duration leading to a faster atrial conduction may be the cause of this clinical observation.
Modeling Atrial Arrhythmias: Impact on Clinical Diagnosis and Therapies
TLDR
The state-of-the-art of computer models of the electrical dynamics of the atria are reviewed and the evolving role of simulation in assisting the clinical diagnosis and treatment of atrial arrhythmias is discussed.
Left to Right Atrial Electrophysiological Differences: Substrate for a Dominant Reentrant Source during Atrial Fibrillation
TLDR
The authors' simulations show that shorter refractoriness in the LA translates into a shorter period of spiral rotation, and as a result, reentry in theLA dominates the overall excitation patterns in the atria.
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  • P. Platonov, L. Mitrofanova, L. V. Chireikin, S. Olsson
  • Medicine
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
  • 2002
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