Interactome Networks and Human Disease

@article{Vidal2011InteractomeNA,
  title={Interactome Networks and Human Disease},
  author={Marc Vidal and Michael E. Cusick and Albert-L{\'a}szl{\'o} Barab{\'a}si},
  journal={Cell},
  year={2011},
  volume={144},
  pages={986-998}
}
Complex biological systems and cellular networks may underlie most genotype to phenotype relationships. Here, we review basic concepts in network biology, discussing different types of interactome networks and the insights that can come from analyzing them. We elaborate on why interactome networks are important to consider in biology, how they can be mapped and integrated with each other, what global properties are starting to emerge from interactome network models, and how these properties may… CONTINUE READING
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