Interactions of tumour-targeting nanoparticles with proteins: potential of using capillary electrophoresis as a direct probe.

@article{Aleksenko2012InteractionsOT,
  title={Interactions of tumour-targeting nanoparticles with proteins: potential of using capillary electrophoresis as a direct probe.},
  author={Svetlana S. Aleksenko and Alexei Y Shmykov and Sławomir Oszwałdowski and Andrei R Timerbaev},
  journal={Metallomics : integrated biometal science},
  year={2012},
  volume={4 11},
  pages={1141-8}
}
Metal-based nanoscale particles possess unique optoelectronic or magnetic properties that make them highly promising as imaging agents in cancer therapy research. The fate of nanoparticles in vivo and particularly, the delivery to tumours are closely related to their interactions with plasma proteins. Furthermore, proteins can be used to modify the nanoparticle surface in order to facilitate active targeting to tumours. Therefore, there is an ongoing need for new and more capable analytical… CONTINUE READING