Interactions of thyroid hormone and FSH in the regulation of rat granulosa cell apoptosis.

@article{Zhang2011InteractionsOT,
  title={Interactions of thyroid hormone and FSH in the regulation of rat granulosa cell apoptosis.},
  author={Cheng Zhang and G. P. Xia and Benjamin K-T Tsang},
  journal={Frontiers in bioscience},
  year={2011},
  volume={3},
  pages={1401-13}
}
Thyroid hormone (TH) is important for normal reproductive function. Our previous studies indicate that FSH increases preantral follicle growth in vitro, a response markedly enhanced by triiodothyronine (T3). However, the nature of this hormonal interaction is poorly understood. The objective of this study was to determine if and how T3 modulate FSH-induced expression and actions of granulosa cell intracellular survival and death intermediates. We investigated the possible involvement of Src and… CONTINUE READING
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