Interactions of renin-angiotensin system gene polymorphisms and antihypertensive effect of benazepril in Chinese population.

Abstract

AIM Angiotensin-converting enzyme inhibitors are widely used antihypertensive drugs with individual response variation. We studied whether interactions of AGT, AGTR1 and ACE2 gene polymorphisms affect this response. MATERIALS & METHODS Our study is based on a 3-year field trial with 1831 hypertensive patients prescribed benazepril. Generalized multifactor… (More)
DOI: 10.2217/pgs.11.2

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