Interactions of presynaptic Ca2+ channels and snare proteins in neurotransmitter release.

@article{Catterall1999InteractionsOP,
  title={Interactions of presynaptic Ca2+ channels and snare proteins in neurotransmitter release.},
  author={William A. Catterall},
  journal={Annals of the New York Academy of Sciences},
  year={1999},
  volume={868},
  pages={144-59}
}
N- and P/Q-type Ca2+ channels are localized in high density in presynaptic nerve terminals and are crucial elements in neuronal excitation-secretion coupling. In addition to mediating Ca2+ entry to initiate transmitter release, they are thought to interact directly with proteins of the synaptic vesicle docking/fusion machinery. These Ca2+ channels can be purified from brain as a complex with SNARE proteins, which are involved in exocytosis. In addition, N-type and P/Q-type Ca2+ channels are… CONTINUE READING
96 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 96 extracted citations

Similar Papers

Loading similar papers…