Interactions of ethyl-beta-carboline-3-carboxylate and Ro 15-1788 with CGS 8216 in an animal model of anxiety.

@article{File1983InteractionsOE,
  title={Interactions of ethyl-beta-carboline-3-carboxylate and Ro 15-1788 with CGS 8216 in an animal model of anxiety.},
  author={S. E. File and Richard G. Lister},
  journal={Neuroscience letters},
  year={1983},
  volume={39 1},
  pages={91-4}
}
The effect of CGS 8216 (10 mg/kg) alone and in combination with the imidazodiazepine Ro 15-1788 (10 mg/kg) or ethyl-beta-carboline-3-carboxylate (beta-CCE 1 mg/kg) was tested in the social interaction test of anxiety. All 3 compounds were found to have an anxiogenic action. When Ro 15-1788 or beta-CCE was combined with CGS 8216, no mutual antagonism of the drugs' effects was observed. The failure of Ro 15-1788 to antagonize the anxiogenic action of CGS 8216 raises the possibility that CGS 8216… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

A review of 25 years of the social interaction test.

European journal of pharmacology • 2003
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…