Interactions of bovine neurophysins with neurohypophyseal hormones. On the role of tyrosine-49.

Abstract

Reaction of tetranitromethane with the lone tyrosine residue of bovine neurophysin I and II, tyrosine-49, gave nitro derivatives of these proteins which were obtained in a highly purified form by preparative electrophoresis. Equilibrium dialysis experiments indicated clearly that oxytocin binding remained essentially unaffected by the chemical modification… (More)

Topics

5 Figures and Tables

Cite this paper

@article{Wolff1975InteractionsOB, title={Interactions of bovine neurophysins with neurohypophyseal hormones. On the role of tyrosine-49.}, author={Jan Wolff and Robert Alazard and M Camier and John H. Griffin and Pinchas Cohen}, journal={The Journal of biological chemistry}, year={1975}, volume={250 13}, pages={5215-20} }