Interactions of Indocyanine Green and Lipid in Enhancing Near-Infrared Fluorescence Properties: The Basis for Near-Infrared Imaging in Vivo

@inproceedings{Kraft2014InteractionsOI,
  title={Interactions of Indocyanine Green and Lipid in Enhancing
Near-Infrared Fluorescence Properties: The Basis for Near-Infrared
Imaging in Vivo},
  author={John C. Kraft and Rodney J. Y. Ho},
  booktitle={Biochemistry},
  year={2014}
}
Indocyanine green (ICG) is a near-infrared (NIR) contrast agent commonly used for in vivo cardiovascular and eye imaging. For medical diagnosis, ICG is limited by its aqueous instability, concentration-dependent aggregation, and rapid degradation. To overcome these limitations, scientists have formulated ICG in various liposomes, which are spherical lipid membrane vesicles with an aqueous core. Some encapsulate ICG, while others mix it with liposomes. There is no clear understanding of lipid… CONTINUE READING