Interactions of 2,3‐benzodiazepines and cydothiazide at AMPA receptors: patch clamp recordings in cultured neurones and area CA1 in hippocampal slices

@article{Rammes1996InteractionsO2,
  title={Interactions of 2,3‐benzodiazepines and cydothiazide at AMPA receptors: patch clamp recordings in cultured neurones and area CA1 in hippocampal slices},
  author={G. Rammes and D. Swandulla and G. Collingridge and S. Hartmann and C. Parsons},
  journal={British Journal of Pharmacology},
  year={1996},
  volume={117}
}
1 The 2,3‐benzodiazepines GYKI 52466, GYKI 53405 and GYKI 53655 antagonized AMPA‐induced currents in cultured superior colliculus neurones in a non use‐dependent manner (steady state IC50S: GYKI 52466 9.8±0.6 μm; GYKI 53405 3.1±0.6 μm; GYKI 53655 0.8±0.1 μm). 2 Higher concentrations of all three antagonists slowed the onset kinetics and quickened the offset kinetics of AMPA‐induced currents indicative of an allosteric interaction with the AMPA recognition site. 3 Cydothiazide (3–300 μm… Expand
53 Citations
Effects of the potent ampakine CX614 on hippocampal and recombinant AMPA receptors: interactions with cyclothiazide and GYKI 52466.
  • 104
  • PDF
Cyclothiazide and AMPA receptor desensitization: analyses from studies of AMPA‐induced release of [3H]‐noradrenaline from hippocampal slices
  • 19
  • Highly Influenced
Interactions of GYKI 52466 and NBQX with cyclothiazide at AMPA receptors: experiments with outside-out patches and EPSCs in hippocampal neurones
  • 24
  • PDF
Differential modulation of AMPA receptor mediated currents by Evans Blue in postnatal rat hippocampal neurones
  • 14
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 87 REFERENCES
Glutamate-activated currents in outside-out patches from spiny versus aspiny hilar neurons of rat hippocampal slices
  • 63
  • PDF
...
1
2
3
4
5
...