Interactions involving the human RNA polymerase II transcription/nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein.

@article{Iyer1996InteractionsIT,
  title={Interactions involving the human RNA polymerase II transcription/nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein.},
  author={Narayan P Iyer and Michael S. Reagan and K. John Wu and Bertram J. Canagarajah and Errol C. Friedberg},
  journal={Biochemistry},
  year={1996},
  volume={35 7},
  pages={
          2157-67
        }
}
  • Narayan P Iyer, Michael S. Reagan, +2 authors Errol C. Friedberg
  • Published 1996
  • Biology, Medicine
  • Biochemistry
  • The human basal transcription factor TFIIH plays a central role in two distinct processes. TFIIH is an obligatory component of the RNA polymerase II (RNAP II) transcription initiation complex. Additionally, it is believed to be the core structure around which some if not all the components of the nucleotide excision repair (NER) machinery assemble to constitute a nucleotide excision repairosome. At least two of the subunits of TFIIH (XPB and XPD proteins) are implicated in the disease xeroderma… CONTINUE READING

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