Interactions between the Nse3 and Nse4 Components of the SMC5-6 Complex Identify Evolutionarily Conserved Interactions between MAGE and EID Families

@inproceedings{Hudson2011InteractionsBT,
  title={Interactions between the Nse3 and Nse4 Components of the SMC5-6 Complex Identify Evolutionarily Conserved Interactions between MAGE and EID Families},
  author={Jessica J. R. Hudson and Katerina Bednarova and Lucie Koz{\'a}kov{\'a} and Chunyan Liao and Marc Guerineau and Rita Colnaghi and Susanne Vidot and Jarom{\'i}r Marek and Sreenivas Reddy Bathula and A. R. Lehmann and Jan Palecek},
  booktitle={PloS one},
  year={2011}
}
BACKGROUND The SMC5-6 protein complex is involved in the cellular response to DNA damage. It is composed of 6-8 polypeptides, of which Nse1, Nse3 and Nse4 form a tight sub-complex. MAGEG1, the mammalian ortholog of Nse3, is the founding member of the MAGE (melanoma-associated antigen) protein family and Nse4 is related to the EID (E1A-like inhibitor of… CONTINUE READING