Interactions between the NO-citrulline cycle and brain-derived neurotrophic factor in differentiation of neural stem cells.

Abstract

The diffusible messenger NO plays multiple roles in neuroprotection, neurodegeneration, and brain plasticity. Argininosuccinate synthase (AS) is a ubiquitous enzyme in mammals and the key enzyme of the NO-citrulline cycle, because it provides the substrate L-arginine for subsequent NO synthesis by inducible, endothelial, and neuronal NO synthase (NOS). Here… (More)
DOI: 10.1074/jbc.M111.338095

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Cite this paper

@article{Lameu2012InteractionsBT, title={Interactions between the NO-citrulline cycle and brain-derived neurotrophic factor in differentiation of neural stem cells.}, author={Claudiana Lameu and Cleber A Trujillo and Telma T Schwindt and Priscilla D Negraes and Micheli M Pillat and K{\'a}tia L. P. Morais and Ivo Lebrun and Henning Ulrich}, journal={The Journal of biological chemistry}, year={2012}, volume={287 35}, pages={29690-701} }