Interactions between sleep, stress, and metabolism: From physiological to pathological conditions.

@article{Hirotsu2015InteractionsBS,
  title={Interactions between sleep, stress, and metabolism: From physiological to pathological conditions.},
  author={Camila Hirotsu and Sergio Brasil Tufik and M{\^o}nica Levy Andersen},
  journal={Sleep science},
  year={2015},
  volume={8 3},
  pages={143-52}
}
Poor sleep quality due to sleep disorders and sleep loss is highly prevalent in the modern society. Underlying mechanisms show that stress is involved in the relationship between sleep and metabolism through hypothalamic-pituitary-adrenal (HPA) axis activation. Sleep deprivation and sleep disorders are associated with maladaptive changes in the HPA axis, leading to neuroendocrine dysregulation. Excess of glucocorticoids increase glucose and insulin and decrease adiponectin levels. Thus, this… CONTINUE READING
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