Interactions between sleep, circadian function, and glucose metabolism: implications for risk and severity of diabetes

@article{Reutrakul2014InteractionsBS,
  title={Interactions between sleep, circadian function, and glucose metabolism: implications for risk and severity of diabetes},
  author={Sirimon Reutrakul and Eve van Cauter},
  journal={Annals of the New York Academy of Sciences},
  year={2014},
  volume={1311}
}
Sleep disturbances, including sleep insufficiency and sleep fragmentation, have been linked to abnormal glucose metabolism and increased diabetes risk. Well‐controlled laboratory studies have provided insights regarding the underlying mechanisms. Several large prospective studies suggest that these sleep disturbances are associated with an increased risk of incident diabetes. Obstructive sleep apnea, which combines sleep fragmentation and hypoxemia, is a major risk factor for insulin resistance… 
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Current evidence supporting the contributions that sleep disorders play in the development of obesity, insulin resistance, and T2DM as well as possibly influences on glycemic control in type 1 diabetes are reviewed, with a special focus on data in pediatric populations.
Sleep Disorders and Gestational Diabetes Mellitus
Type 1 Diabetes, Sleep, and Hypoglycemia
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There is a need to develop sleep promotion programs and test their effects on sleep, glucose, and related outcomes (e.g., self-care, psychological health) and support sleep interventions in improving sleep and glycemic control while diabetes technology use could potentially improve sleep.
Metabolic Consequences of Obstructive Sleep Apnea Especially Pertaining to Diabetes Mellitus and Insulin Sensitivity
TLDR
The bidirectional correlation between OSA and diabetes is outlined and the pathophysiologic mechanisms by approaching their basic etiologies are explored.
Assessment of Sleep Quality in Patients with Type 2 Diabetes Mellitus: A Case-control Study
TLDR
It was found that sleep duration leads impaired glucose metabolism and that irregular sleep pattern plays role in the onset of abnormal eating behaviors by affecting glucose metabolism adversely and playing an important role inThe pathophysiology of T2DM.
Sleep Control, GPCRs, and Glucose Metabolism
Role of sleep quality in the metabolic syndrome
TLDR
This work critically and extensively review the published literature and provides a comprehensive overview of the most salient pathophysiologic pathways underlying the links between sleep, sleep disorders, and cardiometabolic functioning.
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