Interactions between nuclei and the cytoskeleton are mediated by SUN-KASH nuclear-envelope bridges.

@article{Starr2010InteractionsBN,
  title={Interactions between nuclei and the cytoskeleton are mediated by SUN-KASH nuclear-envelope bridges.},
  author={Daniel A Starr and Heidi N. Fridolfsson},
  journal={Annual review of cell and developmental biology},
  year={2010},
  volume={26},
  pages={421-44}
}
The nuclear envelope links the cytoskeleton to structural components of the nucleus. It functions to coordinate nuclear migration and anchorage, organize chromatin, and aid meiotic chromosome pairing. Forces generated by the cytoskeleton are transferred across the nuclear envelope to the nuclear lamina through a nuclear-envelope bridge consisting of SUN (Sad1 and UNC-84) and KASH (Klarsicht, ANC-1 and Syne/Nesprin homology) proteins. Some KASH-SUN combinations connect microtubules, centrosomes… CONTINUE READING
Highly Influential
This paper has highly influenced 21 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 217 extracted citations

Shaping the Endoplasmic Reticulum into a Social Network.

Trends in cell biology • 2016
View 8 Excerpts
Highly Influenced

As the fat flies: The dynamic lipid droplets of Drosophila embryos.

Biochimica et biophysica acta • 2015
View 7 Excerpts
Highly Influenced

LINCing the nuclear envelope to gametogenesis.

Current topics in developmental biology • 2013
View 8 Excerpts
Highly Influenced

Nuclear Positioning

View 7 Excerpts
Highly Influenced

Cellular mechanisms of nuclear migration

View 6 Excerpts
Highly Influenced

Nuclear Envelope-Associated Chromosome Dynamics during Meiotic Prophase I

Front. Cell Dev. Biol. • 2017
View 4 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 69 references

Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization.

Proceedings of the National Academy of Sciences of the United States of America • 2009
View 4 Excerpts
Highly Influenced

The TOR 1 A ( DYT 1 ) gene family and its role in early onset torsion dystonia

LJ Ozelius, CE Page, C Klein, JW Hewett, M Mineta
Genomics • 1999
View 8 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…