Interactions between multiple cell types in parallel microfluidic channels: monitoring platelet adhesion to an endothelium in the presence of an anti-adhesion drug.

@article{Ku2008InteractionsBM,
  title={Interactions between multiple cell types in parallel microfluidic channels: monitoring platelet adhesion to an endothelium in the presence of an anti-adhesion drug.},
  author={Chia-Jui Ku and Teresa D'amico Oblak and Dana M Spence},
  journal={Analytical chemistry},
  year={2008},
  volume={80 19},
  pages={
          7543-8
        }
}
A simple method for immobilizing endothelial cells in the channels of a microfluidic device fabricated with soft lithography is presented that requires no surface oxidation of the substrate material used in conjunction with the microfluidic device and is operable even with a reversible seal. Specifically, optimal conditions for culturing bovine pulmonary artery endothelial cells (bPAECs) to the surface of a Petri dish were investigated. The parameters investigated included fibronectin… CONTINUE READING

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