Interactions between lymphoid tumor cells and isolated liver endothelial cells.

  title={Interactions between lymphoid tumor cells and isolated liver endothelial cells.},
  author={E B Roos and A. J. Tulp and O P Middelkoop and I. V. Van de Pavert},
  journal={Journal of the National Cancer Institute},
  volume={72 5},
Interactions were studied between highly metastatic murine MB6A lymphosarcoma cells and rat liver endothelial cells that had been isolated by collagenase perfusion and purified by unit gravity sedimentation. Experiments were performed on the day of isolation. MB6A cells were observed to adhere to the endothelial cells. Addition of rat serum had a striking effect: The endothelial cells spread over the MB6A cell surface, engulfing the tumor cells. The factor involved was nondialyzable and also… CONTINUE READING

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