Interactions between human complement components factor H, factor I and C3b.

Abstract

Using a microtitre plate assay, direct binding between complement factors I and H was demonstrated, and ligand blotting indicated that factor H interacts with the heavy chain of factor I. Similarly, direct C3(NH3)-factor I and C3(NH3)-factor H binding was characterized [where C3(NH3) is a form of C3 that is cleaved by factor I in the presence of factor H… (More)

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Cite this paper

@article{Soames1997InteractionsBH, title={Interactions between human complement components factor H, factor I and C3b.}, author={Carol-Ann Soames and Rosalind Sim}, journal={The Biochemical journal}, year={1997}, volume={326 ( Pt 2)}, pages={553-61} }