Interactions between growth factor receptors and adhesion molecules: breaking the rules.

@article{Comoglio2003InteractionsBG,
  title={Interactions between growth factor receptors and adhesion molecules: breaking the rules.},
  author={Paolo Maria Comoglio and Carla Boccaccio and Livio Trusolino},
  journal={Current opinion in cell biology},
  year={2003},
  volume={15 5},
  pages={565-71}
}
Adhesion molecules, although catalytically inactive, are able to translate environmental cues into complex intracellular signals. They can do this by associating with tyrosine kinase receptors for growth factors, which can prime, integrate or feedback adhesion-based signals. Recent results show that reciprocal crosstalk between the two systems is only one facet of such a collaboration, and that unconventional and alternative hierarchies can be established in which, on the one hand, cell… CONTINUE READING