Interactions between genetic polymorphisms in the apoptotic pathway and environmental factors on esophageal adenocarcinoma risk.

@article{Wu2011InteractionsBG,
  title={Interactions between genetic polymorphisms in the apoptotic pathway and environmental factors on esophageal adenocarcinoma risk.},
  author={I-Chen Wu and Yang Zhao and Rihong Zhai and Chen-yu Liu and Feng Chen and Monica Ter-Minassian and Kofi Asomaning and Li Su and Rebecca Suk Heist and Matthew H. Kulke and Geoffrey L. Liu and David C. Christiani},
  journal={Carcinogenesis},
  year={2011},
  volume={32 4},
  pages={502-6}
}
How genetic variations in apoptosis pathway interact with environmental factors to contribute to esophageal adenocarcinoma (EA) risk has not been comprehensively investigated. We conducted a case-only analysis in 335 Caucasian EA patients that were genotyped for 242 single nucleotide polymorphisms (SNPs) in 43 apoptotic genes. Gene-environment interactions… CONTINUE READING