Interactions between genetic background, insulin resistance and β-cell function.


An interaction between genes and the environment is a critical component underlying the pathogenesis of the hyperglycaemia of type 2 diabetes. The development of more sophisticated techniques for studying gene variants and for analysing genetic data has led to the discovery of some 40 genes associated with type 2 diabetes. Most of these genes are related to… (More)
DOI: 10.1111/j.1463-1326.2012.01650.x