Interactions between endothelin-I-induced contractions and bronchodilators in human isolated bronchi.

@article{Clayton1997InteractionsBE,
  title={Interactions between endothelin-I-induced contractions and bronchodilators in human isolated bronchi.},
  author={Robert A Clayton and Jane E Nally and Neil C Thomson and John C. McGrath},
  journal={Clinical science},
  year={1997},
  volume={93 6},
  pages={527-33}
}
1. The aim of this study was to compare the ability of four different bronchodilators (atrial natriuretic peptide, salbutamol, sodium nitroprusside and isosorbide dinitrate) to reverse and also to protect against contractions evoked by the spasmogens endothelin-1 and methacholine in human isolated bronchial rings. 2. Contractions evoked by either endothelin-1 or methacholine were reversed by atrial natriuretic peptide (10(-9)-10(-6) mol/l), salbutamol (10(-9)-10(-5) mol/l), sodium nitroprusside… CONTINUE READING

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