Interactions between cytokines and nitric oxide.

  title={Interactions between cytokines and nitric oxide.},
  author={F Y Liew},
  journal={Advances in neuroimmunology},
  volume={5 2},
  • F Y Liew
  • Published 1995 in Advances in neuroimmunology
There is now an impressive range of evidence supporting the important role of cytokines in sleep regulation (see Krueger et al., 1995; De Simoni et al., 1995). It has also been reported that inhibition of nitric oxide (NO) synthesis suppresses sleep in rabbits (Kapás et al., 1994). This is not surprising, since NO is closely involved in neurotransmission (Garthwaite, 1991; Schuman and Madison, 1994) and cytokines are the major inducers of NO synthesis (Hibbs et al., 1990). Further, it is now… CONTINUE READING

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