Interactions between cancer cells and normal cells via miRNAs in extracellular vesicles

Abstract

MicroRNAs (miRNAs) exhibit many functions in biological activities. Recent studies have shown that miRNAs exist outside cells and are transferred between cells. Extracellular miRNAs are protected from ribonucleases found in body fluids through binding to specific proteins or by being encapsulated in lipid bilayer vesicles. Here, we review the mechanisms of… (More)
DOI: 10.1007/s00018-014-1811-0

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