Interactions between cancer cell populations in vivo : cooperation vs competition

@inproceedings{Fuzeta2016InteractionsBC,
  title={Interactions between cancer cell populations in vivo : cooperation vs competition},
  author={Miguel de Almeida Fuzeta and Miguel Godinho Ferreira and Rita Fior and Nuno Bernardes},
  year={2016}
}
Evidence of intratumor heterogeneity was found in a variety of cancers, shown to be composed of subclones with different phenotypes. These subclones are able to establish interactions that are barely understood nowadays and may yield relevant implications for cancer progression. Here, two colorectal cancer cell lines derived from the same patient, one from the primary tumor (SW480) and another from a metastatic site (SW620), established a cooperative interaction when both were injected in… CONTINUE READING