Interactions between calcium and reactive oxygen species in pulmonary arterial smooth muscle responses to hypoxia.


In contrast to the systemic vasculature, where hypoxia causes vasodilation, pulmonary arteries constrict in response to hypoxia. The mechanisms underlying this unique response have been the subject of investigation for over 50 years, and still remain a topic of great debate. Over the last 20 years, there has emerged a general consensus that both increases… (More)
DOI: 10.1016/j.resp.2010.08.014


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