Interactions between antibacterial agents of the quinolone group and nitrofurantoin.


Plate diffusion tests showed that nitrofurantoin antagonized the activity of nalidixic acid, norfloxacin, ciprofloxacin and enoxacin against many Gram-negative bacilli, including all Proteus mirabilis and Klebsiella aerogenes strains tested. No interaction was exhibited when nitrofurantoin and the newer quinolones were tested against Pseudomonas aeruginosa… (More)


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